The purpose of the research was to study the effect of albumin solution on the level of pro- and anti-inflammatory cytokines in women with moderate and severe preeclampsia. Materials and methods. 60 women aged 18 to 40 with moderate and severe preeclampsia were randomized into two groups (30 patients each). Patients of the group I received standard fluid therapy, group II — intensive fluid therapy (similar to one received by women of the group I) in combination with continuous infusion of 20% albumin solution (10 ml/h on the 1st day; 8 ml/h on the 2nd and 3rd days) and furosemide (0.05 mg/kg/h on the 1st day; 0.025 mg/kg/h on 2nd and 3rd days) for 72 hours simultaneously. The concentration of IL-6 and IL-10 was checked before delivery, on the 1st and 3rd days of the postpartum period. Results. On the 3rd day of standard infusion therapy, IL-6 level was 3.5 times higher than the normal ranges and IL-10 level remained 2.3 times lower than in healthy non-pregnant women. Adding albumin solution helped to reduce the IL-6 concentration by 2.3 times in contrast to the initial level and increase IL-10 significantly. Conclusions. Using albumin solution infusion in women with preeclampsia in the postpartum period decreases the index of pro-inflammatory activity, which is the evidence of its anti-inflammatory effect.