Objective: to determine the features of the intestinal microbiota (species, quantitative composition) in salmonellosis, depending on age. Materials and methods. 60 patients with salmonellosis (for the period from 2018 to 2020) were selected for bacteriological examination of feces. These patients were divided into two groups: 1^st — children <1 year of age, 2^nd — children >1 year of age and adults. Bacteriological examination of feces was performed in accordance with acting orders and methodical recommendations. Results. The intestinal microbiota of children from 1st group is characterized by the presence of Staphylococcus aureus (>10⁴ CFU/g) (47%), a variety of bacteria of the families Morganellaceae and Enterobacteriaceae (>10⁴ CFU/g) (82%) and the association conditionally-pathogenic bacteria: Klebsiella spp. with Proteus spp. (5.8%). Intestinal candidiasis was found in 58.8% of children. The number of lacto- and bifidumbacteria in all children from 1st group was within normal limits. No child was found without changes in the species and quantitative composition of intestinal microbiota. In 2^nd group, the number of patients with Staphylococcus aureus was much lower (11.6%). Bacteria of the families Morganellaceae and Enterobacteriaceae were found in 27%. Candida spp. was found in 16%. The number of lacto- and bifidumbacteria was within normal limits. 4% of patients did not have any changes in the species and quantitative composition of intestinal microbiota. Conclusions. It is established that in both studied groups there are changes in the intestinal microbiocenosis of different severity. A characteristic feature of 1^st group is the presence of Staphylococcus aureus in almost half of children, a wide variety of conditionally-pathogenic enterobacteria and bacteria of the genus Proteus, yeast-like fungi of the genus Candida. In 2^nd group dysbiotic processes are less pronounced, compared to 1^st group: the presence of three times less conditionally-pathogenic enterobacteria and bacteria of the genus Proteus, 4 times less — Staphylococcus aureus and 3.7 times less — Candida spp.