The aim: To study clinical manifestations in patients with ulcerative colitis (UC) and concomitant arterial hypertension (AH). Object and methods of the study. A total of 142 patients were examined. There were 76 men (53.5%) and 66 women (46.5%). The minimum age of patients was 19 years, the maximum — 59 years. In 96 of them, a colonoscopy with biopsy was performed and UC was diagnosed (67.6%). Blood pressure measurements revealed AH in 95 of the patients (66.9%). Thus, three groups were formed: «UC+AH» (34.5%); «UC without AH» (33.10%); «AH without UC» (32.4%); followed by a thorough medical history and identification of the leading complaints. Results. This study showed that the main complaints such as abdominal pain, diarrhea, weight loss, subfibrillation were observed in more patients in the «UC+AH» and «UC without AH» groups due to the presence of UC and its absence in patients of the «AH without UC» group (p<0.05). Headache, palpitations, chest pain were more frequent in the «UC+AH» and «AH without UC» groups, due to the presence of AH in these two groups and the absence of AH in the «UC without AH» group (p<0.05). Conclusion. Symptoms in UC and concomitant AH are not specific, but the comorbidity of these two conditions can worsen the course of the disease. The presence of hypertension in patients with UC can worsen the course of the latter, so it requires timely diagnosis and control by both the patient and the doctor.