Evaluation of the quality of life in patients with coronary heart disease with impaired metabolism of vitamin D and homocysteine in the remote postoperative period after coronary artery bypass grafting

December 4, 2020

Objective — to assess the dynamics of the quality of life in patients with coronary heart disease with impaired metabolism of vitamin D and homocysteine after coronary artery bypass grafting (CABG).

Materials and methods. CABG was performed on 126 patients with coronary heart disease. Patients completed the SF-36 quality of life questionnaire upon admission to the department and after 6 and 12 months after surgery.

Results. In patients after CABG who received additional metabolic therapy, as a rule, there were no relapses of angina pectoris, improvement in the quality of life persisted both in the early and long-term periods (up to 3 years of follow-up). In patients with recurrent angina pectoris after CABG, both in the preoperative and in the long-term periods, the quality of life indicators significantly differed from the level of ideal health. The most significant impairments were indicators of mental health, physical functioning and social relations sphere.

Conclusions. In patients after CABG, the SF-36 questionnaire can provide a reliable and sensitive assessment of quality of life. Correction of metabolic disorders and lipid metabolism disorders is essential for patients who have undergone surgery on the heart vessels. Correction of metabolic disorders should be started immediately after surgery.


  • Gandzyuk V.A. (2014) Analysis of ailment on the coronary heart disease in Ukraine. Ukr. Cardiol. J., 3: 45–52.
  • GBD 2015 Mortality and Causes of Death Collaborators (2016) Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980–2015: a systematic analysis for the Global Burden of Disease Study 2015. Lancet, 388(10053): 1459–1544. doi: 10.1016/S0140-6736(16)31012-1.
  • Montalescot G., Sechtem U., Achenbach S. et al. (2013) 2013 ESC guidelines on the management of stable coronary artery disease: the Task Force on the management of stable coronary artery disease of the European Society of Cardiology. Eur. Heart J., 34(38): 2949–3003. doi: 10.1093/eurheartj/eht296.
  • Ware J.E., Snow K.K., Kosinski M., Gandek B. (1993) SF-36 Health Survey Manual and Interpretation Guide. The Health Institute, Boston, MA.
  • Windecker S., Kolh Ph., Alfonso F. et al. (2014) 2014 ESC/EACTS Guidelines on myocardial revascularization: The Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS) Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur. Heart J., 35(37): 2541–2619. doi: 10.1093/eurheartj/ehu278.