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Патогенетические подтипы транзиторных ишемических атак: клиническое течение, формулирование диагноза
Резюме. Цель работы — выделить основные патогенетические подтипы транзиторных ишемических атак (ТИА), определить особенности их клинического течения, взаимосвязь между ними и изменениями ткани головного мозга, оценить объем, продолжительность и обратимость неврологического дефицита у пациентов с разными подтипами заболевания. Обследованы 103 пациента с установленным диагнозом ТИА. По механизму развития выделены атеротромботический, кардиоэмболический, лакунарный, гемодинамический патогенетический подтип заболевания. Описаны характерные клинико-неврологические особенности разных подтипов ТИА, определены частота выявления новых очагов ишемии ткани головного мозга, объем, продолжительность, обратимость неврологического дефицита у больных с разными патогенетическими подтипами ТИА.
Ключевые слова: транзиторные ишемические атаки, патогенетический подтип, клинические проявления, диагностика
Pathogenetic subtypes of transient ischaemic attacks: clinical course, the formulation of a diagnosis
Summary. The main aim of our research is to identify major pathogenetic subtypes of transient ischemic attacks (TIA), to determine the peculiarities of their clinical course, the relationship between them and the changes in brain tissue, to assess the scope, duration and reversibility of neurological deficits in patients with different subtypes of disease. We examined 103 patients with a diagnosis of TIA. There are atherotrombotic, cardioembolic, lacunar, hemodynamic pathogenetic subtype subject to the mechanism of development the disease. We described the typical clinical and neurological features of different subtypes of TIA, identified the frequency of detection of new foci of brain ischemia, the amount, duration, reversibility of neurological deficiency in patients with different pathogenetic subtypes of TIA.
Key words: transient ischemic attack, pathogenetic subtype, clinical manifestations, diagnostics