Modern approaches to the treatment of patients with chronic obstructive pulmonary disease

Objective: to study beta-glucans 1,3 and 1,6 as part of the dietary supplement Immunsil^® D3 in patients with frequent exacerbations of chronic obstructive pulmonary disease (COPD).

Object and methods of research. 42 patients with COPD (group C according to GOLD classification) who had 2–4 clinical exacerbations during the previous year were monitored for 1 year. Patients of the 1st group (n=22) received tiotropium bromide and standard treatment of exacerbations, according to the COPD treatment protocol, the 2nd group (n=20) at the beginning of the observation additionally used Immunsil^® D3 1 caps. 2 times a day for 1 month.

Results. The use of the dietary supplement Immunsil^® D3 contributed to an increase in the number of cells with the activity of natural killers and cells of the monocyte-macrophage series (CD14), as well as the restoration of the immunoregulatory index. Dietary supplementation use reduced the exacerbation of COPD and significantly reduced the need for antibiotics in patients with COPD within the next year after treatment.

Conclusion. Use of dietary supplement Immunsil^® D3 1caps. 2 times a day for 1 month may be recommended for patients with COPD with frequent clinical exacerbations (groups C and D).

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