Cognitive dysfunction and hypertension: literature review and own experience

The article summarizes available data linking arterial hypertension (AG) to cognitive dysfunction, dementia. In own study we also found that AG significantly increases the incidence of cognitive dysfunction in middle-aged persons (49.8±9.0 years). We selected 59 patients with AG of 2–3 degrees (the average level of systolic and diastolic blood pressure 166±13 and 97±6 mm Hg, respectively) (1st group) and 30 practically healthy individuals with normal level of blood pressure (2nd group). Neuropsychological examination was carried out by General Practitioner Assessment of Cognition (GPCOG), Mini-Mental State Examination (MMSE) and Schulte table. Significant cognitive decline was found in patients in the 1st group (MMSE 26.6±1.8, GPCOG 6.9±1.4, Schulte’s test 52.3±10.7; p<0.05). Such results correspond to mild and moderate cognitive dysfunction. There was no cognitive dysfunction in the 2nd group (MMSE 28.9±1.0, GPCOG 8.3±1.4, Schulte’s test 33.4±4.2).

DOI 10.32471/umj.1680-3051.131.142189

Published: 16.05.2019

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