Features of broncho-obstructive syndrome in patients with chronic obstructive pulmonary diseases in connection with active and diseased pulmonary tuberculosis

10 серпня 2018
1035
Спеціальності :
Резюме

The article analyzes the severity of the broncho-obstructive syndrome (BOS) in 111 patients with chronic obstructive pulmonary disease (COPD), depending on the presence of active pulmonary tuberculosis (PT), residual changes after cured PT (RCPT). All patients had a general clinical trial, a bacteriological study on tuberculosis, an examination of the function of external respiration. It was noted that BOS was significantly lower in patients with combined COPD and PT, whereas ΔFV1 after salbutamol test and the severity of clinical symptoms were higher compared to patients with COPD and in combination with RCPT. In women with COPD and in combination with RCPT, BOS was higher in comparison with men, and with the combined pathology of COPD and PT, a reverse trend was observed, which may be due to the number of «bug-years».

N.V. Zhovanyk

Key words: chronic obstructive pulmonary disease, pulmonary tuberculosis, residual changes after cured pulmonary tuberculosis, broncho-obstructive syndrome.

Published: 05.09.2018

References:

  • Vakhnenko A.V., Moisieieva N.V., Kapustianska A.A. (2013) Osoblyvosti etiolohichnykh faktoriv ta perebihu khronichnoho obstruktyvnoho zakhvoriuvannia lehen u khvorykh, shcho nalezhat do riznykh statevykh hrup. Svit med. biol., 2: 200–204.
  • Baker M.A., Lin H.H., Chang H.Y., Murray M.B. (2012) The risk of tuberculosis disease among persons with diabetes mellitus: a prospective cohort study. Clin. Infect. Dis., 54: 818–825.
  • Byrne A.L., Marais B.J, Mitnick C.D. et al. (2015) Tuberculosis and chronic respiratory disease: a systematic review. 32: 138–146.
  • Ghimire H.B., Li J.G. (2011) Impact of pulmonary tuberculosis infection on chronic obstructive pulmonary disease. Eur. Resp. J., 38: 4070.
  • GOLD (2014) Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease, 93 р.
  • Hooper R., Burney P., Vollmer W.M. et al. (2012) Risk factors for COPD spirometrically defined from the lower limit of normal in the BOLD project. Eur. Resp. J., 39: 1343–1353.
  • Kaplan A., Thomas M. (2017) Screening for COPD: the gap between logic and evidence. Eur. Respir. Rev., 26(143): 160113.
  • Kotsiou O.S., Zouridis S., Kosmopoulos M., Gourgoulianis K.I. (2018) Impact of the financial crisis on COPD burden: Greece as a case study. Eur. Respir. Rev., 27(147): 170106.
  • Lamprecht B., McBurnie M.A., Vollmer W. et al. (2011) COPD in Never Smokers Results From the Population-Based Burden of Obstructive Lung Disease Study. Chest, 4: 752–763.
  • Lee C.H., Shu C.C., Lim C.S. et al. (2013) Risk factors for pulmonary tuberculosis in patients with chronic obstructive airway disease in Taiwan: a nationwide cohort study. BMC Infect. Dis., 13: 194.
  • Perez-Padilla R., Fernandez R., Lopez Varela M. et al. (2012) Airflow obstruction in never smokers in five Latin American cities: the PLATINO study. Arch. Med. Res., 43: 159–165.
  • van Buul A.R., Kasteleyn M.J., Chavannes N.H., Taube C. (2017) Association between morning symptoms and physical activity in COPD: a systematic review. Eur. Respir. Rev., 26(143): 160033.