A retrospective information search of literary sources was carried out using the spatial-vector model of the descriptor system, supplemented by a manual search of the literature lists of included articles. Materials and methods. Obtaining literary scientific information was carried out using the information search systems Scopus, Google Scholar, CrossRef and PubMed. Results and their discussion. It has been determined that left ventricular function is acutely reduced within 24 hours of burn injury and remains depressed for up to 72 hours and may persist for years. Myocardial ischemia and microvascular dysfunction occur when myocardial oxygen demand exceeds supply. Dyshydria has a significant impact on the cardiovascular system. Depletion of the endothelial glycocalyx leads to fluid loss. In extensive burns, serum catecholamines and corticosteroids are elevated 10- to 50-fold and persist for a long time. The hypermetabolic response to severe burn injury can lead to muscle protein breakdown. Expression of immune-dependent genes causes burn-related cardiac dysfunction and leads to persistent cardiac stress. Systemic release of inflammatory mediators contributes to organ dysfunction. Accumulation of calcium, reactive oxygen species, and nitrogen leads to cardiomyocyte damage. Conclusion. Burns cause long-term cardiovascular disorders that can last up to 2–3 years after the injury or more. Ignoring the possibility of long-term cardiac consequences of minor burns leads to increased length of hospitalization, repeated medical visits, and material costs for treatment.