Cardiovascular risk control requires not only timely diagnosis and appropriate pharmacotherapy but also sustained treatment adherence, regular monitoring, and timely therapy adjustment. The article discusses major barriers to adequate blood pressure control, including poor adherence and therapeutic inertia. Particular attention is paid to home blood pressure monitoring, assessment of adherence, patient–physician communication, and follow-up planning. The importance of treatment accessibility, including reimbursement programs, is also considered as a factor that may support long-term therapy. A comprehensive approach combining evidence-based treatment, monitoring, and adherence support may improve cardiovascular risk control.