Ultrasound densitometry: frequency of osteopenia in children with scoliosis I degree and osteopenic syndrome

October 25, 2024
193
УДК:  616-053.2+616.71-007.234
Resume

The purpose is to study the presence of osteopenia and the condition of bone tissue in children with scoliosis of the first degree by the method of ultrasound densitometry.

Object and methods of research. 39 children (23 girls and 16 boys) aged 7–12 years (average age 10.5±1.9 years) were examined, who in the winter of 2024 took vitamin D for 1 month in prophylactic doses. The diagnosis of scoliosis of the first degree was established based on the results of X-Ray of the spine in direct projection and the results of the computer screening photo-geometric program «Posture». The condition of the bone tissue was studied by the method of ultrasonic densitometry of the calcaneus using the Sonost 2000 device, the frequency of the linear built-in sensor being 0.5 MHz.

Results. According to the results of ultrasound densitometry of the calcaneus of children 7–12 years old, there were no difference in indicators between boys and girls, as well as by age. So 67% of children with scoliosis of the first degree had initial manifestations of osteopenia (Z-criterion — –1.2 ±0.03).

Conclusions. The examination plan of children with scoliosis of the first degree should include ultrasound densitometry. Osteopenia is characterized by a decrease in the mineral density of bone tissue, which can lead to an increase in the angle of deformation of the spine. There is a question about the development of a treatment complex already for scoliosis of the first degree, which will include calcium preparations, vitamin D in appropriate doses in course doses and exercises that will strengthen the back muscles, in order to prevent the progression of scoliosis.

References

  • 1. Дичко В., Дичко О. (2019) Ефективність впливу фізичних реабілітаційних заходів на показники функціонального стану хребта дітей молодшого шкільного віку 7–10 років зі сколіозом. Професіоналізм педагога: теоретичні й методичні аспекти, (10): 65–71. doi.org/10.31865/2414-9292.10.2019.182144.
  • 2. Le Fever D., Menger R.P. (2024) Infantile and Juvenile Scoliosis. Treasure Island (FL): StatPearls Publishing. http://www.ncbi.nlm.nih.gov/books/NBK519498/.
  • 3. Peng Y., Wang S.R., Qiu G.X. et al. (2020) Research progress on the etiology and pathogenesis of adolescent idiopathic scoliosis. Chinese Med. J., 133: 483–493. DOI: 10.1097/CM9.0000000000000652.
  • 4. Studer D., Hasler C.C. (2024) Diagnostic and therapeutic strategies in early onset scoliosis: A current concept review. Journal of children’s orthopaedics, 18(2): 113–123. doi.org/10.1177/18632521241228141.
  • 5. Bondar K., Nguyen A., Vatani J. et al. (2021) The Demographics and Epidemiology of Infantile, Juvenile, and Adolescent Idiopathic Scoliosis in a Southern California Integrated Health Care System. Spine, 46(21): 1468–1477. doi.org/10.1097/BRS.0000000000004046.
  • 6. Essex R., Dibley L. (2024) Adolescent idiopathic scoliosis: treatment outcomes, quality of life and implications for practice. Nursing children and young people. Advance online publication. doi.org/10.7748/ncyp.2024.e1510 1.
  • 7. Menger R.P., Sin A.H. (2024) Adolescent Idiopathic Scoliosis. Treasure Island (FL): Stat. Pearls Publishing; Jan- from: http://www.ncbi.nlm.nih.gov/books/NBK499908.
  • 8. Wang L., Huang P., Du H. et al. (2022) Assessment of bone densitometry using radiography with a step-wedge phantom: a pilot study of the forearm. Quantitative imaging in medicine and surgery, 12(6): 3340–3350. doi.org/10.21037/qims-21-842.
  • 9. Del Prete C.M., Tarantin D., Viva M.G. et al. (2024) Spinal Orthosis in Adolescent Idiopathic Scoliosis: An Overview of the Braces Provided by the National Health Service in Italy. Medicina, 60(1): 3. doi.org/10.3390/medicina60010003.
  • 10. Медична статистика МОЗ України. З medstat.gov.ua/ukr/statdanMMXIX.html.
  • 11. molbuk.ua/vashe_zdorovya/p_zdorovya/90401-skolioz-u-ditey-yak-borotysya.html#google_vignette.
  • 12. Гамма Т.В., Григус І.М., Орел І.О. та ін. (2022) Фізична терапія дітей віком 10–12 років зі сколіозом ІІ ступеня. Rehabilitation and Recreation, (11): 10–17. doi.org/10.32782/2522-1795.2022.11.1.
  • 13. Поляруш І.А., Василенко Є.В., Кобінський О.В. (2022) Огляд сучасних підходів до застосування засобів фізичної терапії при сколіотичній хворобі у підлітків. Спортивна медицина, фізична терапія та ерготерапія, 2: 125–131.
  • 14. Afanasieva I.O., Khaitovych М.V., Potaskalova V.S. et al. (2020) The prevalence of posture pathology in school-aged children (results of a population-based study with the use of the computerized photo-geometric program «Posture». Запорожский мед. журн., 22, 3 (120): 389–394. DOI: 10.14739/2310-1210.2020.3.204948.
  • 15. Cao J., Sun W., Zheng Y. et al. (2024) Global Health Epidemiology Research Group (GHERG) Variations in the prevalence of scoliosis by age, sex, geographic region, and subtype among Chinese children: A systematic review and modelling study. J. Global Health, 14: 04062. doi.org/10.7189/jogh.14.04062.
  • 16. Fainardi V., Nora M., Salghetti A. et al. (2024) Prevalence of Scoliosis in Children and Adolescents with Cystic Fibrosis. Children, 11(3): 321.
  • 17. turanturan.com.tr.
  • 18. Ізюмець О.І., Лайко Л.І., Ройзман А.Ф. й ін. (2016) Заходи з виявлення остеопенії у дітей та підлітків. Совр. педиатр., 5(77): 30–32. doi: 10.15574/SP.2016.77.30.
  • 19. Thomas J.J., Stans A.A., Milbrandt T.A. et al. (2021) Trends in Incidence of Adolescent Idiopathic Scoliosis: A Modern US Population-based Study. J. Pediatr. Orthopedics, 41(6): 327–332. doi.org/10.1097/BPO.0000000000001808.
  • 20. Kim D.S., Lee J.S. (2023) Vitamin D in adolescent idiopathic scoliosis: a meta-analysis. BMC Musculoskeletal. Disord., 24: 689. doi.org/10.1186/s12891-023-06793-0.
  • 21. Єрмак Т.А. (2001) Остеопенічний синдром у дітей, хворих на ідіопатичний сколіоз [дисертація]. Харків. ДУ «Інститут патології хребта та суглобів ім. проф. М.І. Сітенка НАМН України».
  • 22. Марушко Ю.В., Волоха Т.І., Асонов А.О. (2016) Остеопенічний синдром у дітей із хронічним гастродуоденітом. Совр. педиатр., 2(74): 134–138.
  • 23. Montero-Odasso M., van der Velde N., Martin F.C. et al.; Task Force on Global Guidelines for Falls in Older Adults (2022) World guidelines for falls prevention and management for older adults: a global initiative. Age Ageing, 51(9): afac205.
  • 24. Eid R., Abdelsalam M., Fathy A.A. et al. (2023) Bone mineral density in egyptian children with juvenile idiopathic arthritis: possible correlation to serum RANKL/osteoprotegerin (OPG) ratio and OPG gene polymorphisms. Pediatric rheumatology, 21(1): 58. doi.org/10.1186/s12969-023-00843-6.
  • 25. Madhuchani D., Seneviratne S.N., Ward L.M. (2023) Bone health in childhood and adolescence: an overview on dual-energy X-ray absorptiometry scanning, fracture surveillance and bisphosphonate therapy for low-middle-income countries. Frontiers in endocrinology, 14: 1082413. doi.org/10.3389/fendo.2023.1082413.
  • 26. Hanafy N.M., Elsehaimy L.A., Alzokm S.M. et al. (2022) Bone mineral density and risk factors of osteoporosis in children. Egypt. Rheumatologist., 3(44): 257–260.
  • 27. Maeda S.S., Peters B.S.E., Martini L.A. et al. (2022) Official position of the Brazilian Association of Bone Assessment and Metabolism (ABRASSO) on the evaluation of body composition by densitometry: part I (technical aspects) — general concepts, indications, acquisition, and analysis. Advances in Rheumatology, 62: 7.
  • 28. Alawi M., Begum A., Harraz M. et al. (2021) Dual-Energy X-Ray Absorptiometry (DEXA) Scan Versus Computed Tomography for Bone Density Assessment. Cureus, 13(2): e13261. doi.org/10.7759/cureus.13261.
  • 29. Cherian K.E., Kapoor N., Meeta M. et al. (2021) Dual-Energy X-Ray Absorptiometry Scanning in Practice, Technical Aspects, and Precision Testing. Journal of mid-life health, 12(4): 252–256. doi.org/10.4103/jmh.jmh_215_21.
  • 30. Haseltine K.N., Chukir T., Smith P.J. et al. (2021) Bone Mineral Density: Clinical Relevance and Quantitative Assessment. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 62(4): 446–454.
  • 31. Sağlam Y., Bingöl I., Yaşar N.E. et al.; Turkish Ministry of Health, Pediatric Orthopaedic Scientific Survey Group (2024) The burden of scoliosis: a nationwide database study on demographics, incidence, and surgical rates. European spine journal: official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 33(2): 655–662. doi.org/10.1007/s00586-023-07967-z.
  • 32. Wu Z., Zhu X., Xu L. et al. (2023) More Prevalent and Severe Low Bone-Mineral Density in Boys with Severe Adolescent Idiopathic Scoliosis Than Girls: A Retrospective Study of 798 Surgical Patients. J. Clin. Med., 12(8): 2991.
  • 33. Yang Y., Chen Z., Huang Z. et al. (2023) Risk factors associated with low bone mineral density in children with idiopathic scoliosis: a scoping review. BMC musculoskeletal disorders., 24(1): 48. doi.org/10.1186/s12891-023-06157-8.
  • 34. Ісакова О., Колесніченко О. (2024) Використання показників денситометрії кісткової тканини для оптимізації діагностики та лікування дітей у стоматології. Via Stomatologiae, 1(1): 58–67.
  • 35. Anwar F., Iftekhar H., Taher T. et al. (2019) Dual Energy X-ray Absorptiometry Scanning and Bone Health: The Pressing Need to Raise Awareness Amongst Pakistani Women. Cureus, 11(9): e5724. doi.org/10.7759/cureus.5724.
  • 36. Jang M.J., Shin C., Kim S. et al. (2023) Factors affecting bone mineral density in children and adolescents with secondary osteoporosis. Annals of pediatric Endocrinol. Metabol., 28(1): 34–41. doi.org/10.6065/apem.2244026.013.
  • 37. Al-Agha A.E., Kabli Y.O., Al-Beiruty M.G. et al. (2019) Determinants of bone mineral density through quantitative ultrasound screening of healthy children visiting ambulatory paediatric clinics. Saudi Med. J., 40(6): 560–567.
  • 38. Ferjani H.L., Cherif I., Nessib D.B. et al. (2024) Pediatric and adult osteoporosis: a contrasting mirror. Annals of pediatric endocrinology & metabolism, 29(1): 12–18.
  • 39. Fogelman I., Blake G.M. (2000) Different Approaches to Bone Densitometry. Journal of nuclear medicine: official publication. Society of Nuclear Medicine, 41(12): 2015–2025.
  • 40. Li X., Hung V.W.Y., Yu F.W.P. et al. (2020) Persistent low-normal bone mineral density in adolescent idiopathic scoliosis with different curve severity: A longitudinal study from presentation to beyond skeletal maturity and peak bone mass. Bone, 133: 115217. doi.org/10.1016/j.bone.2019.115217.
  • 41. Deshpande N., Hadi M.S., Lillard J.C. et al. (2023) Alternatives to DEXA for the assessment of bone density: a systematic review of the literature and future recommendations. Journal of neurosurgery. Spine, 38(4): 436–445.
  • 42. Nishida M., Yagi M., Suzuki S. et al. (2023) Persistent low bone mineral density in adolescent idiopathic scoliosis: A longitudinal study. Journal of orthopaedic science: official journal of the Japanese Orthopaedic Association., 28(5): 1099–1104. doi.org/10.1016/j.jos.2022.07.005.
  • 43. Patel M., Razzouk J., Shin D. et al. (2024) Association Between Vertebral Bone Quality Score and Dual-Energy X-ray Absorptiometry for the Assessment of Bone Mineral Density in Adolescent Patients. Cureus, 16(2): e53402.
  • 44. Ramos O., Razzouk J., Chung J.H. et al. (2022) Opportunistic assessment of bone density in patients with adolescent idiopathic scoliosis using MRI-based vertebral bone quality. Journal of clinical neuroscience: official journal of the Neurosurgical Society of Australasia, 103: 41–43. doi.org/10.1016/j.jocn.2022.06.030.
  • 45. Ge Q., Zhang L., Sun Z. et al. (2023) The mediation effect of vitamin A and vitamin D supplement in the association between serum vitamin K levels and musculoskeletal disorders in preschool children. Frontiers in nutrition, 10: 1239954.
  • 46. Hampton M., Brewer P., Athanassacopoulos M. et al. (2022) Prevalence and Significance of Vitamin D Deficiency in Patients Undergoing Corrective Surgery for Adolescent Idiopathic Scoliosis. Int. J. Spine Surg., 16(1): 202–207.
  • 47. Herdea A., Dragomirescu M.C., Ulici A. et al. (2022) Controlling the Progression of Curvature in Children and Adolescent Idiopathic Scoliosis Following the Administration of Melatonin, Calcium, and Vitamin D. Children (Basel, Switzerland), 9(5): 758.
  • 48. Llopis-Ibor C.I., Mariscal G., de la Rubia Ortí J.E. et al. (2023) Incidence of vitamin D deficiency in adolescent idiopathic scoliosis: a meta-analysis. Frontiers in endocrino­logy, 14: 1250118. doi.org/10.3389/fendo.2023.1250118.
  • 49. Lim D.B.N., Moon R.J., Davies J.H. (2022) Advances in Diagnosis and Management of Childhood Osteoporosis. Journal of clinical research in pediatric endocrinology, 14(4): 370–384. doi.org/10.4274/jcrpe.galenos.2022.2022-8-3.
  • 50. Sakka S.D., Cheung M.S. (2020) Management of primary and secondary osteoporosis in children. Therapeutic advances in musculoskeletal disease, 12: 1759720X20969262. doi.org/10.1177/1759720X20969262.