Analysis of the incidence and clinical manifestations of the post-COVID syndrome: implications for modern medical research | Ukrainian Medical Journal

The study of the incidence of COVID-19 and the clinical manifestations of post-Covid syndrome included a systematic review of scientific papers, screening of abstracts, and quality assessment based on publications in leading medical journals. Using the RT-PCR technique, the study revealed a variety of clinical manifestations from asymptomatic to severe conditions. It is noted that about 40% of infected people have no symptoms, while the majority have mild symptoms. Critical conditions requiring intensive therapy are observed in approximately 5% of patients. Further clinical observations have shown that long-term symptoms can haunt patients much longer than the initial period of recovery, in the form of post-covid syndrome, which includes a large group of symptoms such as fatigue, shortness of breath, impaired smell and taste. These symptoms have long-term dynamics and can cause serious complications, in particular in the lungs, cardiovascular system, and even lead to neuropsychiatric disorders. It was found that mental disorders and long-term cognitive dysfunctions registered among patients require the intervention of specialized medical services for adequate treatment and social support. In order to provide comprehensive care, the development of individualized rehabilitation plans involving multidisciplinary teams, including physical therapists and psychologists, is recommended. The study also highlights the need for enhanced medical surveillance, differential diagnosis, and optimization of treatment and rehabilitation strategies, given the long-term impact of COVID-19 on patient health. Asignificant emphasis is placed on the medical and psychological approach to the treatment of post-covid complications, with special attention to mental disorders that may arise as a result of infection and social isolation. Prospects for further research are focused on the development of standardized protocols for the diagnosis, monitoring and treatment of post-covid syndrome, which is critical for improving the medical care of this category of patients.

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