Known and unknown possibilities of moxonidine

September 5, 2022
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The article examines the problem of arterial hypertension (AH), the most common non-infectious disease in the world, which has priority in the development of such cardiovascular complications as stroke and myocardial infarction, which cause the increase in disability and premature mortality of the population. A review of current literature data on approaches to the treatment of patients with AH was conducted, with an emphasis on the thera­peutic potential of the imidazoline receptor agonist moxonidine, which is currently the most commonly used antihypertensive drug with a central mechanism of action. It is noted that the necessary requirements for prescribing antihypertensive drugs should be their high antihypertensive efficacy, organ protection, synergistic interaction with other classes of antihypertensive drugs, good tolerability, positive or at least neutral effect on lipid and carbohydrate metabolism. A study of the properties of moxonidine on a fairly large sample of patients with AH and associated metabolic disorders showed high antihypertensive effectiveness of the drug both as part of combined therapy and separately.

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