Proteflazid® vs COVID-19: successes in research

October 29, 2021

The original antiviral drug Proteflazid® has been used in clinical practice since the early 2000s for the etiotropic treatment of acute respiratory viral diseases due to its ability to block of RNA- and DNA-polymerases viruses. Given that at the beginning of the global pandemic COVID-19 caused by RNA-containing virus of the species SARS-CoV-2 in 2020, the ability of the active substance of the drug to inhibit the activity of 3CL-protease coronavirus SARS-CoV-2 and subsequently confirm the property of the active substance to block the replication of SARS-CoV-2 virus in cell cultures in vitro, it has been extremely important to test the effectiveness of the drug Proteflazid®, drops, for the prevention and treatment of COVID-19 in «off label use». In retrospective clinical studies, it has been shown that Proteflazid® in the conditions of the COVID-19 pandemic contributes to a 2.2-fold reduction in the proportion of sick medical staff, reduction in the proportion of patients with severe disease by 3.3 times, reduction of the average duration of treatment by 1.8 times and the most important is that there is no mortality among the sick medical staff and patients who has administered the drug.


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