Acquired hemophilia A: current approaches to treatment and clinical cases

October 25, 2021
1048
Resume

Classical hemophilia is an X-linked disease of the hemostasis system characterized by decreased or impaired synthesis of coagulation factors. Most doctors believe that hemophilia is a hereditary pathology, but in clinical practice, in addition to the hereditary form, there is acquired hemophilia, which is an extremely rare pathology, based on the production of autoantibodies that inactivate coagulation factors. The article presents a literature review on key aspects of the management of patients with hemophilia, focusing on the problem of acquired hemophilia A, as well as our own clinical observations of successful treatment of patients with inhibitors to coagulation factors.

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