Risk factors and prevention of thrombosis in patients with COVID-19

April 28, 2021

The article presents a review of the literature on the study of risk factors and prevention of thrombosis in patients with COVID-19. COVID-19 coagulopathy is characterized by increased levels of fibrinogen and D-dimer, moderate thrombocytopenia and slight increase of prothrombin time. The main risk factors that increase the probability of thromboembolic events are old age (>60 years), male gender, hypertension, diabetes and obesity. For standard stratification of thrombosis risk in modern conditions, it is necessary to use a modified IMPROVE scale, which is the most optimal for use in patients with COVID-19 and takes into account all indicators for calculating the risk of thromboembolism in such patients. The use of low molecular weight heparins is indicated to prevent thrombosis in patients with COVID-19. Taking anticoagulants after discharge from the hospital may be considered if there is a high risk of thrombosis and a low risk of bleeding. The question of taking antiplatelet agents to reduce the risk of thrombosis remains open and needs further study.


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