Clinical case of severe bilateral pneumonia associated with SARS-CoV-2 viral infection

April 26, 2021

Coronavirus infection spreads rapidly and is transmitted from person to person by airborne and contact-household routes. A positive polymerase chain reaction (PCR) test for SARS-CoV-2 is required for a definitive diagnosis. However, multi-slice computed tomography (MSCT) is a sensitive and specific method of diagnosing coronavirus lung disease as the most common manifestation of infection. In addition, in patients at high risk of COVID-19, signs of viral pneumonia in MSCT of the lungs may precede negative PCR results. Based on our own experience and observations in the diagnosis of severe respiratory syndrome SARS-CoV-2, we draw attention to the need to perform MSCT of the chest in patients at high risk and clinical manifestations of COVID-19-associated pneumonia, despite the initial negative PCR result.


  • 1. Carotti M., Salaffi F., Sarzi-Puttini P. (2020) Chest CT features of coronavirus disease 2019 (COVID-19) pneumonia: key points for radiologists. Radiol. Med., 125: 636–646.
  • 2. Kwee Th.C., Kwee R.M. (2020) Chest CT in COVID-19: What the Radiologist Needs to Know. Radiographics, 40(7): 1848–1865. doi: 10.1148/rg.2020200159
  • 3. Boryshevska-Lohin O.A., Ahii V.І., Akar S.I. et al. (2020) Method for diagnosing COVID-19 pneumonia. Patent № 145093. [In Ukr.].
  • 4. Lee E.Y.P., Ng M.-Y., Khonga P.-L. (2020) COVID-19 pneumonia: what has CT taught us? Lancet Infect. Dis., 20(4): 384–385.