Modern approaches to etiopathogenesis, diagnosis and treatment of purulent-inflammatory diseases of the pelvic organs (literature review) | Ukrainian Medical Journal

Sytnіk P.O.

Main
Publications
Modern approaches to etiopathogenesis, diagnosis and treatment of purulent-inflammatory diseases of the pelvic organs (literature review)

Modern approaches to etiopathogenesis, diagnosis and treatment of purulent-inflammatory diseases of the pelvic organs (literature review)

September 21, 2020

632

Obstetrics and Gynecology

Surgery

Sytnіk P.O.

Keywords :

antibiotic resistance,

bacterial vaginosis,

human papilloma virus,

opportunistic flora,

ovarian cancer,

predictors of inflammation severity,

purulent-inflammatory diseases of the pelvic organs,

risk factors,

sexually transmitted diseases

Specialities :

Obstetrics and Gynecology

Surgery

Resume

The article presents a modern analysis of the pathophysiology of pelvic inflammatory disease (PID), a review of scientific research on the diagnosis, analysis of severity, treatment of PID and generalized risk factors, including bacterial vaginosis, intrauterine inseminations and intrauterine contraceptive pills with levonorgestrel. The relationship between PID and an increased risk of ovarian cancer has been analyzed. A literature review covering the diagnosis and analysis of predictors of the severity of PID is carried out.

References:

Buralkina N.A., Katkova A.S., Arutyunova E.E. i dr. (2018) Vospalitelnyie zabolevaniya organov malogo taza: patogeneticheskie aspektyi, diagnostika, klinika, lechenie (obzor literaturyi). Ginekologiya, 20(3): 12–15. DOI: 10.26442/2079-5696_2018.3.12-15.
Burka O.A., Tutchenko T.M., Pedachenko N.Iu., Kudlai O.M. (2020) Suchasni pidkhody do vyboru antybakterialnykh preparativ pry zapalnykh protsesakh tazovykh orhaniv: rol innovatsiinykh mikrobiolohichnykh metodiv ohliad literatury. Reprodukt. endokrynol., 1(51): 25–31. DOI: dx.doi.org/10.18370/2309-4117.2020.51.25-31.
Hryhoriev Ye.O., Sytnik P.O., Diakov A.V., Sytnik O.H. (2020) Analiz mikrobnoho spektra u zhinok z hniino-zapalnymy zakhvoriuvanniamy orhaniv maloho taza v umovakh nadannia urhentnoi operatyvnoi hinekolohichnoi dopomohy z urakhuvanniam faktoriv ryzyku. Zdorove zhenshchynы, 3(149): 38–41.
Dikke G.B. (2017) Znachenie oralnoy kontratseptsii v profilaktike retsidivov bakterialnogo vaginoza i snizhenii riska vospalitelnyih zabolevaniy organov malogo taza. Probl. reproduk., 23(4): 32–36. DOI: 10.17116/repro201723432-36.
Dobrohotova Yu.E., Bondarenko K.R., Dvornikov A.S. (2016) Sovremennyie predstavleniya o vospalitelnyih protsessah organov malogo taza. Ginekologiya, 18(3): 4–8.
Ziganshin A.M., Mudrov V.A. (2019) Optimizatsiya kompleksnoy terapii vospalitelnyih zabolevaniy organov malogo taza u zhenschin. Ginekologiya, 21(3): 30–34. DOI: doi.org/10.26442/20795696.2019.3.190465.
Kudekenova S.B., Mustafina A.A., Alekseeva T.A., Mustafina G.G. (2015) Patogeneticheskie osobennosti profilaktiki gnoyno-septicheskih oslozhneniy v akusherstve i ginekologii. Vest. novgorod. gos. un-ta, 2(85): 130–132.
Kuznetsov R.E., Skripchenko D.V. (2019) Vospalitelnyie zabolevaniya organov malogo taza: sostoyanie problemyi. Consilium Medicum, 21(6): 92–96. DOI: 10.26442/20751753.2019.6.190565.
Nurgalieva E.V., Duhin A.O., Guschin A.E. (2016) Mikrobiota zhenskih polovyih organov pri gnoyno-vospalitelnyih zabolevaniyah genitaliy. RUDN. Seriya Meditsina, 2: 197–201.
Ostrovskiy V.K., Makarov S.V., Yangolenko D.V. i dr. (2011) Pokazateli krovi i leykotsitarnyiy indeks intoksikatsii pri otsenke tyazhesti techeniya i opredelenii prognoza vospalitelnyih, gnoynyih i gnoyno-destruktivnyih zabolevaniy organov bryushnoy polosti i legkih. Ulyanov. med.-biol. zhurn., 1: 73–78.
Pestrikova T.Yu., Yurasov I.V., Yurasova E.A. (2018) Vospalitelnyie zabolevaniya organov malogo taza: sovremennyie trendyi i diagnostiki i terapii (obzor literaturyi). Ginekologiya, 20(6): 35–41. DOI: 10.26442/20795696.2018.6.180072.
Pisarev V.V., Lvov S.E. (2012) Gematologicheskie pokazateli intoksikatsii pri otsenke tyazhesti techeniya i ranney diagnostike vospalitelnyih oslozhneniy u bolnyih s perelomami dlinnyih kostey konechnostey. ortoped. Rossii, 2(64): 41–47.
Podolskyi Vl.V., Podolskyi V.V. (2017) Suchasni mozhlyvosti likuvannia khronichnykh zapalnykh zakhvoriuvan statevykh orhaniv u zhinok fertylnoho viku. Zdorove zhenshchynы, 5: 132–136.
Rozhkovska N.M., Sytnik P.O. (2016) Prohnozuvannia ryzyku uskladnen zapalnykh protsesiv orhaniv maloho taza u zhinok. Bukovyn. med. visn., 20(3): 147–150.
Rozhkovska N.M., Sytnik P.O., Holubenko M.Iu., Sadovnycha O.O. (2017) Leikotsytarni indeksy u prohnozuvanni klinichnykh naslidkiv zapalnykh protsesiv zhinochykh statevykh orhaniv. Akt. pyt. pediatr. akusher. hinekol., 2: 78–83.
Utkin E.V. (2009) Taktika lecheniya bolnyih s gnoynyimi vospalitelnyimi zabolevaniyami pridatkov matki. Mat i ditya v Kuzbasse, 2(37): 30–36.
Shlyapnikov M.E., Kuznetsova L.V., Tarasova A.V. (2018) Effektivnost primeneniya deeskalatsionnoy stupenchatoy kombinirovannoy antibakterialnoy terapii v kompleksnom lechenii patsientok s tyazhelyimi infektsionno-vospalitelnyimi zabolevaniyami matki i ee pridatkov. Vest. med. in-ta «REAVIZ», 2: 82–86.
Eastman A.J., Bergin I.L., Chai D. et al. (2018) Impact of the Levonorgestrel-Releasing Intrauterine System on the Progression of Chlamydia trachomatis Infection to Pelvic Inflammatory Disease in a Baboon Model. J. Infect. Dis., 217(4): 656–666. DOI: doi.org/10.1093/infdis/jix545.
Banerjee S., Tian T., Wei Z. et al. (2017) The ovarian cancer oncobiome. Oncotarget., 8: 36225–36245. DOI: doi.org/10.18632/oncotarget.16717.
Birgisson N.E., Zhao Q., Secura G.M. et al. (2015) Positive Testing for Neisseria gonorrhoeae and Chlamydia trachomatis and the Risk of Pelvic Inflammatory Disease in IUD Users. J. Womens Health (Larchmt), 24(5): 354–359. DOI: 10.1089/jwh.2015.5190.
Brunham R.C., Gottlieb S.L., Paavonen J. (2015) Pelvic inflammatory disease. N. Engl. J. Med., 372(21): 2039–2048. DOI: 10.1056/NEJMra1411426.
Centers for Disease Control and Prevention (2015) Pelvic Inflammatory Disease (PID) (https://www.cdc.gov/std/tg2015/pid.htm).
Chan G.M.F., Fong Y.F., Ng K.L. (2019) Tubo-Ovarian Abscesses: Epidemiology and Predictors for Failed Response to Medical Management in an Asian Population. Infect. Dis. Obstet. Gynecol., 2019: 4161394. DOI: 10.1155/2019/4161394.
Di Tucci Ch., Di Mascio D., Schiavi M.C. et al. (2018) Pelvic inflammatory disease: possible catches and correct management in young women. Case Reports in Obstetrics and Gynecology (https://doi.org/10.1155/2018/5831029).
Chiou W.Y., Chen C.A., Lee M.S. et al. (2016) Pelvic inflammatory disease increases the risk of a second primary malignancy in patients with cervical cancer treated by surgery alone. Medicine, 95(47): e5409. DOI: doi.org/10.1097/MD.0000000000005409.
Cui L., Sheng Y., Sun M. et al. (2016) Chronic Pelvic Inflammation Diminished Ovarian Reserve as Indicated by Serum Anti Mülerrian Hormone. PLoS ONE 11(6): e0156130. DOI:10.1371/journal.pone.0156130.
Czeyda-Pommersheim F., Kalb B., Costello J. et al. (2017) MRI in pelvic inflammatory disease: a pictorial review. Abdom. Radiol., 42: 935–950. DOI: doi.org/10.1007/s00261-016-1004-4.
El Hentour K., Millet I., Pages-Bouic E. et al. (2018) How to differentiate acute pelvic inflammatory disease from acute appendicitis? A decision tree based on CT findings. Eur. Radiol., 28: 673–682. DOI: doi.org/10.1007/s00330-017-5032-4.
Erenel H., Yilmaz N., Oncul M. et al. (2017) Usefulness of Serum Procalcitonin Levels in Predicting Tubo-Ovarian Abscess in Patients with Acute Pelvic Inflammatory Disease. Gynecol. Obstet. Invest., 82: 262–266. DOI: 10.1159/000449161.
Fortner R.T., Terry K.L., Bender N. et al. (2019) Sexually transmitted infections and risk of epithelial ovarian cancer: results from the Nurses’ Health Studies. Br. J. Cancer, 120: 855–860. DOI: doi.org/10.1038/s41416-019-0422-9.
Haggerty C.L., Totten P.A., Tang G. et al. (2016) Identification of novel microbes associated with pelvic inflammatory disease and infertility. Sex. Transmit. Infect., 92: 441–446. DOI: 10.1136/sextrans-2015-052285.
Huang C.-C., Huang C.-C., Lin S.-Y. et al. (2019) Association of pelvic inflammatory disease (PID) with ectopic pregnancy and preterm labor in Taiwan: A nationwide population-based retrospective cohort study. PLoS ONE, 14(8): e0219351. DOI: doi.org/10.1371/journal.pone.0219351.
Ingerslev K., Hogdall E., Schnack T.H. et al. (2017) The potential role of infectious agents and pelvic inflammatory disease in ovarian carcinogenesis. Infect. Agents Cancer, 12: 25. DOI: doi.org/10.1186/s13027-017-0134-9.
Tymon-Rosario J. (2019) Streptococcus constellatus Peritonitis and Subsequent Septic Shock following Intrauterine Device Removal. Case Reports in Obstetrics and Gynecology. DOI: doi.org/10.1155/2019/6491617.
Karaca K., Ozkaya E., Eken M.K. et al. (2018) Serum procalcitonin levels together with clinical features and inflammatory markers in women with tubo-ovarian abscess for discriminating requirements for surgery for full recovery. J. Obstet. Gynaecol., 38: 818–821. DOI: 10.1080/01443615.2017.1405927.
Nyhus L.M., Vitello J.M., Condom R.E. (1996) Abdominal pain: a guide to rapid diagnosis. Norwalk, 319 p.
Brady P.C. (2016) Handbook of consult and inpatient gynecology. Pelvic inflammatory disease and Tubo-ovarian abscesses. Springer, Berlin, р. 121–133. DOI: 10.1007/978-3-319-27724-0_6.
Piao J., Lee E.J., Lee M. (2020) Association between pelvic inflammatory disease and risk of ovarian cancer: аn updated meta-analysis. Gynecol. Oncol., 157(2): 542–548. DOI: 10.1016/j.ygyno.2020.02.002.
Matorras R., Rubio K., Iglesias M. et al. (2018) Risk of pelvic inflammatory disease after intrauterine insemination: a systematic review. Reproduct. Biomed., 36: 164–171. DOI: doi.org/10.1016/j.rbmo.2017.11.002.
Savaris R.F., Fuhrich D.G., Duarte R.V. et al. (2017) Antibiotic therapy for pelvic inflammatory disease. Cochrane Database of Syst. Rev., 4: CD010285. DOI: 10.1002/14651858.CD010285.pub2.
Stewart L.M., Spilsbury K., Jordan S. et al. (2018) Risk of high-grade serous ovarian cancer associated with pelvic inflammatory disease, parity and breast cancer. Cancer Epidemiol., 55: 110–116. DOI: 10.1016/j.canep.2018.05.011.
Tukeva T.A., Aronen H.J., Karjalainen P.T. et al. (1999) MR imaging in pelvic inflammatory disease: comparison with laparoscopy and US. Radiology, 1(210): 209–216. DOI: 10.1148/radiology.210.1.r99ja04209.
Xie X., Yang M., Ding Y., Chen J. (2017) Microbial infection, inflammation and epithelial ovarian cancer (Review). Oncol. Letters, 14(2): 1911–1919. DOI: 10.3892/ol.2017.6388.
Zaporozhan V. Marichereda V. Sytnik P. (2019) Inflammation biomarkers in pelvic inflammatory disease. Eur. J. Obstet. Gynecol. Reproduct. Biol., 234: e43. doi: org/10.1016/j.ejogrb.2018.08.249.
Zhou Z., Zeng F., Yuan J. et al. (2017) Pelvic inflammatory disease and the risk of ovarian cancer: a meta-analysis. Cancer Causes Control., 28(5): 415–428. DOI: 10.1007/s10552-017-0873-3.