Adaptation possibilities and reactivity in elderly patients against acute intestinal infection caused by nonpathogenic microorganisms, taking into account the leading etiological factor

Objective — to evaluate the adaptive capacity and reactivity in elderly patients with acute intestinal infection (AII) caused by nonpathogenic microorganisms (NM), taking into account the leading etiological factor. Object and research methods. The data of 46 elderly patients with AII caused by NM were analyzed. On the basis of the selected pathogen 3 groups of patients were formed: 1^st (n=26) — with AII caused by enteropathogenic microorganisms, 2^nd (n=6) — representatives of the Pseudomonadaceae, 3^rd (n=14) — Staphylococcus aureus. The adaptation index, leukocyte index, the neutrophil-to-lymphocyte ratio, the neutrophil-to-monocyte ratio were used to evaluate the adaptive capacity of the orga­nism. Results. In patients of the 2^nd group intoxication syndrome has mainly infectious genesis, there were signs of tension of the humoral level of immunity and increased factors of nonspecific reactivity. In the 3^rd group, autoimmune factors of the formation of intoxication syndrome predominated, signs of incompleteness of phagocytosis and delayed type hypersensitivity were observed. Conclusions. Significant differences in the adaptive capacity and reactivity of the elderly patients with AII caused by NM have been proved, taking into account the leading etiological factor.