Late ventricular potentials and morphofunctional condition of heart in elderly hypertensive patients with atrial fibrillation

Aim — to study the relationship between heart structural and functional remodeling and late ventricle potentials (LVPs) as marker of myocardial electrical inhomogeneity in elderly hypertensive patients with atrial fibrillation (AF). Material and methods. Doppler echocardiography and high resolution electrocardiography for LPVs detection were investigated in 106 patients aged 70.1±0.7. There were 20 patients with uncomplicated essential hypertension (EH), 44 patients with persistent (PersAF) and 42 — with permanent (PermAF) AF. Results. The development of AF in elderly hypertensive patients is associated with the increase of myocardial electrical inhomogeneity, which is most expressed in permanent AF: the incidence of LVPs registration in patients with uncomplicated EH, PersAF and PermAF was 15.0; 38.6 and 47.6% respectively. There was an association between myocardial electrical inhomogeneity and greater severity of left ventricular hypertrophy, the larger heart chambers sizes in EH and AF patients. In PermAF patients, there was also dependence between parameters of myocardial electrical inhomogeneity and worsening of left ventricular systolic and diastolic function, and the rise of systolic blood pressure in the pulmonary artery.

Published: 27.12.2016

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