Incidence of Helicobacter pylori infection in acute coronary syndrome patients of different age and gender with pre-existing primary arterial hypertension

August 22, 2018
704
Resume

Aim — to investigate the Helicobacter pylori infection incidence in acute coronary syndrome patients of different age and gender with pre-existing primary arterial hypertension and current dyspepsia complains. Object and methods. 103 patients (age 45–83 years) with acute coronary syndrome, primary arterial hypertension and dyspeptic complaints participated the clinical trial. The patients underwent serum total antibodies to Helicobacter pylori rate detection additionally to the standard diagnosis methods according to the protocol. Results. The incidence of Helicobacter pylori infection was significantly higher among men than women. The myocardial infarction incidence was significantly higher in patients infected with Helicobacter pylori than in uninfected ones, especially in middle-aged and elderly men in comparison to women. This tendency wasn’t present in uninfected patients. Conclusions. The data obtained might indicate a negative impact of Helicobacter pylori infection on the clinical course of acute coronary artery syndrome with pre-existing primary arterial hypertension, providing advisability of Helicobacter pylori infection screening and eradication in middle-aged and elderly in acute coronary artery syndrome patients with pre-existing primary arterial hypertension, especially in male gender.

M.I. Shved, T.M. Hanych

Key words: acute coronary artery syndrome, Helicobacter pylori, age, gender.

Published: 05.09.2018

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